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PRL
2006
130views more  PRL 2006»
13 years 7 months ago
Efficient huge-scale feature selection with speciated genetic algorithm
With increasing interest in bioinformatics, sophisticated tools are required to efficiently analyze gene information. The classification of gene expression profiles is crucial in ...
Jin-Hyuk Hong, Sung-Bae Cho
IDA
2005
Springer
14 years 1 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen
BIOINFORMATICS
2006
82views more  BIOINFORMATICS 2006»
13 years 7 months ago
ZooDDD: a cross-species database for digital differential display analysis
SUMMARY: In this paper, we combined EST information from the UniGene database and orthologous relationships from the Ensembl database to construct a ZooDDD database. The primary f...
Yun-Ching Chen, Chung-Der Hsiao, Wen-Dar Lin, Chun...