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» Missing genes in the annotation of prokaryotic genomes
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BIBE
2010
IEEE
148views Bioinformatics» more  BIBE 2010»
13 years 2 months ago
Prediction of Gene Ontology Annotations Based on Gene Functional Clustering
We propose an algorithm that predicts potentially missing Gene Ontology annotations, in order to speed up the time-consuming annotation curation process. The proposed method extend...
Marco Tagliasacchi, Roberto Sarati, Marco Masserol...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Estimating true evolutionary distances under rearrangements, duplications, and losses
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
Yu Lin, Vaibhav Rajan, Krister M. Swenson, Bernard...
BMCBI
2006
144views more  BMCBI 2006»
13 years 7 months ago
Association algorithm to mine the rules that govern enzyme definition and to classify protein sequences
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...
Shih-Hau Chiu, Chien-Chi Chen, Gwo-Fang Yuan, Thy-...