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BMCBI
2007
174views more  BMCBI 2007»
13 years 8 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2007
127views more  BMCBI 2007»
13 years 8 months ago
Characterization and simulation of cDNA microarray spots using a novel mathematical model
Background: The quality of cDNA microarray data is crucial for expanding its application to other research areas, such as the study of gene regulatory networks. Despite the fact t...
Hye Young Kim, Seo Eun Lee, Min Jung Kim, Jin Il H...
BMCBI
2007
105views more  BMCBI 2007»
13 years 8 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
IJDMB
2008
132views more  IJDMB 2008»
13 years 8 months ago
A Bayesian framework for knowledge driven regression model in micro-array data analysis
: This paper addresses the sparse data problem in the linear regression model, namely the number of variables is significantly larger than the number of the data points for regress...
Rong Jin, Luo Si, Christina Chan
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and e
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...