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BMCBI
2006
111views more  BMCBI 2006»
13 years 6 months ago
High throughput profile-profile based fold recognition for the entire human proteome
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
BMCBI
2005
97views more  BMCBI 2005»
13 years 6 months ago
The yeast kinome displays scale free topology with functional hub clusters
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
Robin E. C. Lee, Lynn A. Megeney
BMCBI
2010
113views more  BMCBI 2010»
13 years 6 months ago
ProbABEL package for genome-wide association analysis of imputed data
Background: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, impute...
Yurii S. Aulchenko, Maksim V. Struchalin, Cornelia...
ECOOP
2006
Springer
13 years 10 months ago
Demeter Interfaces: Adaptive Programming Without Surprises
Adaptive Programming (AP) allows for the separate definition of data structures and traversals with attached computations, performed during the traversal, that operate on these dat...
Therapon Skotiniotis, Jeffrey Palm, Karl J. Lieber...
BMCBI
2005
126views more  BMCBI 2005»
13 years 6 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois