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    BMCBI
    2007
    146views more  BMCBI 2007»
    Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
    13 years 7 months ago
    Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
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    Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
    Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
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    JMLR
    2010
    159views more  JMLR 2010»
    Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks
    13 years 2 months ago
    Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks
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    Networks are becoming a unifying framework for modeling complex systems and network inference problems are frequently encountered in many fields. Here, I develop and apply a gener...
    Nikolai Slavov
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    EJASP
    2010
    132views more  EJASP 2010»
    Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
    13 years 2 months ago
    Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
    Download  www.cs.utsa.edu
    The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
    Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
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    BMCBI
    2007
    143views more  BMCBI 2007»
    Factor analysis for gene regulatory networks and transcription factor activity profiles
    13 years 7 months ago
    Factor analysis for gene regulatory networks and transcription factor activity profiles
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    Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
    Iosifina Pournara, Lorenz Wernisch
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    BMCBI
    2007
    136views more  BMCBI 2007»
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
    13 years 7 months ago
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
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    Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
    Xiaoyu Chen, Mathieu Blanchette
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