Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...