Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
The success of Skype has inspired a generation of peer-topeer-based solutions for satisfactory real-time multimedia services over the Internet. However, fundamental questions, suc...
Breaking news often contains timely definitions and descriptions of current terms, organizations and personalities. We utilize such web sources to construct definitions for such t...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...