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BMCBI
2007
186views more  BMCBI 2007»
13 years 8 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
CIBCB
2009
IEEE
13 years 9 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty
ESCIENCE
2006
IEEE
14 years 2 months ago
A Middleware Framework for Maximum Likelihood Evaluation over Dynamic Grids
We have designed a maximum likelihood fitter using the actor model to distribute the computation over a heterogeneous network. The prototype implementation uses the SALSA program...
Wei-Jen Wang, Kaoutar El Maghraoui, John Cummings,...
BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2007
164views more  BMCBI 2007»
13 years 8 months ago
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...
Peng Li, Chaoyang Zhang, Edward J. Perkins, Ping G...