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BMCBI
2005
88views more  BMCBI 2005»
13 years 8 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...
BCB
2010
175views Bioinformatics» more  BCB 2010»
13 years 3 months ago
Gene set analysis using principal components
We present a new method for identifying gene sets associated with labeled samples, where the labels can be case versus control, or genotype differences. Existing approaches to thi...
Isa Kemal Pakatci, Wei Wang, Leonard McMillan
BMCBI
2010
126views more  BMCBI 2010»
13 years 6 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
CIBCB
2006
IEEE
14 years 2 months ago
A Novel Graphical Model Approach to Segmenting Cell Images
— Successful biological image analysis usually requires satisfactory segmentations to identify regions of interest as an intermediate step. Here we present a novel graphical mode...
Shann-Ching Chen, Ting Zhao, Geoffrey J. Gordon, R...
ECAL
2005
Springer
14 years 2 months ago
Timescale and Stability in Adaptive Behaviour
Recently, in both the neuroscience and adaptive behaviour communities, there has been growing interest in the interplay of multiple timescales within neural systems. In particular,...
Christopher L. Buckley, Seth Bullock, Netta Cohen