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BMCBI
2007
141views more  BMCBI 2007»
15 years 4 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...
JCB
2006
123views more  JCB 2006»
15 years 4 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
SNPD
2008
15 years 5 months ago
An Approach to Modeling Software Safety
: Software for safety-critical systems has to deal with the hazards identified by safety analysis in order to make the system safe, risk-free and fail-safe. Software safety is a co...
M. Ben Swarup, P. Seetha Ramaiah
BMCBI
2010
156views more  BMCBI 2010»
15 years 4 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
TCS
2008
15 years 3 months ago
GemCell: A generic platform for modeling multi-cellular biological systems
The mass and complexity of biological information requires computer-aided simulation and analysis to help scientists achieve understanding and guide experimentation. Although livi...
Hila Amir-Kroll, Avital Sadot, Irun R. Cohen, Davi...