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BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2007
175views more  BMCBI 2007»
13 years 8 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
BMCBI
2010
149views more  BMCBI 2010»
13 years 8 months ago
A multifactorial analysis of obesity as CVD risk factor: Use of neural network based methods in a nutrigenetics context
Background: Obesity is a multifactorial trait, which comprises an independent risk factor for cardiovascular disease (CVD). The aim of the current work is to study the complex eti...
Ioannis K. Valavanis, Stavroula G. Mougiakakou, Ke...
BMCBI
2010
159views more  BMCBI 2010»
13 years 8 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2010
146views more  BMCBI 2010»
13 years 8 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
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