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BMCBI
2002
214views more  BMCBI 2002»
13 years 8 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
ENTCS
2007
82views more  ENTCS 2007»
13 years 8 months ago
A Simple Calculus for Proteins and Cells
The use of process calculi to represent biological systems has led to the design of different formalisms such as brane calculi and κ-calculus. Both have proved to be useful to m...
Cosimo Laneve, Fabien Tarissan
ICCS
2007
Springer
14 years 2 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
APCCM
2009
13 years 9 months ago
Conceptional Modeling and Analysis of Spatio-Temporal Processes in Biomolecular Systems
In life science, deeper understanding of biomolecular systems is acquired by computational modeling and analysis. For the modeling of several kinds of reaction networks, e.g. sign...
Andreas Schäfer, Mathias John
BMCBI
2006
133views more  BMCBI 2006»
13 years 8 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...