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» Modeling splicing sites with pairwise correlations
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BMCBI
2007
102views more  BMCBI 2007»
13 years 11 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
CIBB
2008
14 years 29 days ago
Splice Site Prediction Using Artificial Neural Networks
A system for utilizing an artificial neural network to predict splice sites in genes has been studied. The neural network uses a sliding window of nucleotides over a gene and predi...
Øystein Johansen, Tom Ryen, Trygve Eftest&o...
BMCBI
2006
116views more  BMCBI 2006»
13 years 11 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2007
121views more  BMCBI 2007»
13 years 11 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...