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BMCBI
2006
155views more  BMCBI 2006»
13 years 8 months ago
CAVER: a new tool to explore routes from protein clefts, pockets and cavities
Background: The main aim of this study was to develop and implement an algorithm for the rapid, accurate and automated identification of paths leading from buried protein clefts, ...
Martin Petrek, Michal Otyepka, Pavel Banás,...
BMCBI
2006
112views more  BMCBI 2006»
13 years 8 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
Curation of complex, context-dependent immunological data
Background: The Immune Epitope Database and Analysis Resource (IEDB) is dedicated to capturing, housing and analyzing complex immune epitope related data http:// www.immuneepitope...
Randi Vita, Kerrie Vaughan, Laura Zarebski, Nima S...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2006
118views more  BMCBI 2006»
13 years 8 months ago
Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
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