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BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
BMCBI
2007
183views more  BMCBI 2007»
13 years 7 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
nGASP - the nematode genome annotation assessment project
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
Avril Coghlan, Tristan J. Fiedler, Sheldon J. McKa...
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2010
177views more  BMCBI 2010»
13 years 7 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
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