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» Modelling Developmental Regulatory Networks
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BIB
2008
93views more  BIB 2008»
13 years 8 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
EMO
2005
Springer
108views Optimization» more  EMO 2005»
14 years 1 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
GECCO
2009
Springer
146views Optimization» more  GECCO 2009»
13 years 11 months ago
Evolving specific network statistical properties using a gene regulatory network model
Abstract. The generation of network topologies with specific, userspecified statistical properties is the aim of this paper. This is achieved through the use of an artifical Gene R...
Miguel Nicolau, Marc Schoenauer
CIBCB
2007
IEEE
13 years 12 months ago
Genetic Regulatory Network Modeling Using Network Component Analysis and Fuzzy Clustering
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
Fatemeh Bakouie, Mohammad Hassan Moradi
CMSB
2006
Springer
13 years 11 months ago
Compositional Reachability Analysis of Genetic Networks
Genetic regulatory networks have been modeled as discrete transition systems by many approaches, benefiting from a large number of formal verification algorithms available for the ...
Gregor Gößler