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» Modelling Developmental Regulatory Networks
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GRC
2005
IEEE
14 years 1 months ago
A linear control model for gene intervention in a genetic regulatory network
In this paper, we propose a linear control model for gene intervention in a genetic regulatory network. At each time step, finite controls are allowed to drive the network states...
Shuqin Zhang, Michael K. Ng, Wai-Ki Ching, Tatsuya...
TIT
2010
97views Education» more  TIT 2010»
13 years 2 months ago
Periodic orbits and equilibria in glass models for gene regulatory networks
Abstract--Glass models are frequently used to model gene regulatory networks. A distinct feature of the Glass model is that its dynamics can be formalized as paths through multi-di...
Igor Zinovik, Yury Chebiryak, Daniel Kroening
JCB
2006
114views more  JCB 2006»
13 years 8 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
ECAI
2008
Springer
13 years 9 months ago
Temporal Logic Patterns for Querying Qualitative Models of Genetic Regulatory Networks
Formal verification based on model checking provides a powerful technology to query qualitative models of dynamical systems. The application of model-checking approaches is hamper...
Pedro T. Monteiro, Delphine Ropers, Radu Mateescu,...
HYBRID
2007
Springer
14 years 2 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss