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» Modelling Developmental Regulatory Networks
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BIOWIRE
2007
Springer
14 years 2 months ago
Evolutionary and Temporal Dynamics of Transcriptional Regulatory Networks
Transcriptional regulation is a key mechanism that allows cells to make the appropriate amount of proteins at the right time. This is mediated by transcription factors that respond...
M. Madan Babu
AB
2008
Springer
14 years 2 months ago
Property Preservation along Embedding of Biological Regulatory Networks
In the course of understanding biological regulatory networks (BRN), scientists usually start by studying small BRNs that they believe to be of particular importance to represent a...
Mbarka Mabrouki, Marc Aiguier, Jean-Paul Comet, Pa...
CCE
2008
13 years 8 months ago
Informative gene selection and design of regulatory networks using integer optimization
A central problem in bioinformatics and systems biology is the selection of appropriate models in a rational and systematic way. This fundamentally combinatorial problem can be re...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Ioa...
BMCBI
2007
143views more  BMCBI 2007»
13 years 8 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
RECOMB
2005
Springer
14 years 8 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston