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» Modelling Developmental Regulatory Networks
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BMCBI
2011
12 years 11 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf
CEC
2003
IEEE
14 years 1 months ago
Transcription and evolution of a virtual bacteria culture
Abstract- This paper describes implementation details and results from a simulated multi-agent bacteria ecosystem. Each bacterium is encoded on a DNA-like genome, specifying the ge...
Ricardo M. Hoar, Joanne K. Penner, Christian Jacob
BMCBI
2007
168views more  BMCBI 2007»
13 years 8 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2010
233views more  BMCBI 2010»
13 years 8 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
CMSB
2003
Springer
14 years 1 months ago
An Overview of Data Models for the Analysis of Biochemical Pathways
Biochemical pathways such as metabolic, regulatory or signal tranduction pathways can be viewed as interconnected processes forming an intricate network of functional and physical...
Yves Deville, David Gilbert, Jacques van Helden, S...