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» Modelling Developmental Regulatory Networks
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TCBB
2008
103views more  TCBB 2008»
13 years 8 months ago
DNA Motif Representation with Nucleotide Dependency
The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
Francis Y. L. Chin, Henry C. M. Leung
SDM
2007
SIAM
143views Data Mining» more  SDM 2007»
13 years 9 months ago
Less is More: Compact Matrix Decomposition for Large Sparse Graphs
Given a large sparse graph, how can we find patterns and anomalies? Several important applications can be modeled as large sparse graphs, e.g., network traffic monitoring, resea...
Jimeng Sun, Yinglian Xie, Hui Zhang, Christos Falo...
BMCBI
2007
127views more  BMCBI 2007»
13 years 8 months ago
Characterization and simulation of cDNA microarray spots using a novel mathematical model
Background: The quality of cDNA microarray data is crucial for expanding its application to other research areas, such as the study of gene regulatory networks. Despite the fact t...
Hye Young Kim, Seo Eun Lee, Min Jung Kim, Jin Il H...
BMCBI
2008
150views more  BMCBI 2008»
13 years 8 months ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
ALMOB
2006
113views more  ALMOB 2006»
13 years 8 months ago
Inverse bifurcation analysis: application to simple gene systems
Background: Bifurcation analysis has proven to be a powerful method for understanding the qualitative behavior of gene regulatory networks. In addition to the more traditional for...
James Lu, Heinz W. Engl, Peter Schuster