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BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
DATE
1999
IEEE
120views Hardware» more  DATE 1999»
14 years 24 days ago
Hardware Synthesis from C/C++ Models
Software programming languages, such as C/C++, have been used as means for specifying hardware for quite a while. Different design methodologies have exploited the advantages of f...
Giovanni De Micheli
CIMAGING
2010
195views Hardware» more  CIMAGING 2010»
13 years 10 months ago
SPIRAL out of convexity: sparsity-regularized algorithms for photon-limited imaging
The observations in many applications consist of counts of discrete events, such as photons hitting a detector, which cannot be effectively modeled using an additive bounded or Ga...
Zachary T. Harmany, Roummel F. Marcia, Rebecca Wil...
DATE
1999
IEEE
172views Hardware» more  DATE 1999»
14 years 24 days ago
An Object-Based Executable Model for Simulation of Real-Time Hw/Sw Systems
This paper describes a simulation technique for RealTime Hw/Sw systems based on an object executable model. It allows designers to seamlessly estimate and verify their solutions f...
Olivier Pasquier, Jean Paul Calvez
TOOLS
2000
IEEE
14 years 25 days ago
Design and Implementation of CORBA-Based Subscription Server
The standard CORBA operation invocation model supports synchronous, one-way, and deferred synchronous interactions between clients and servers. However, this model is too restrict...
R. Maheshwari, R. Fatoohi