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BMCBI
2010
105views more  BMCBI 2010»
15 years 2 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
115
Voted
DATE
1999
IEEE
120views Hardware» more  DATE 1999»
15 years 6 months ago
Hardware Synthesis from C/C++ Models
Software programming languages, such as C/C++, have been used as means for specifying hardware for quite a while. Different design methodologies have exploited the advantages of f...
Giovanni De Micheli
CIMAGING
2010
195views Hardware» more  CIMAGING 2010»
15 years 3 months ago
SPIRAL out of convexity: sparsity-regularized algorithms for photon-limited imaging
The observations in many applications consist of counts of discrete events, such as photons hitting a detector, which cannot be effectively modeled using an additive bounded or Ga...
Zachary T. Harmany, Roummel F. Marcia, Rebecca Wil...
DATE
1999
IEEE
172views Hardware» more  DATE 1999»
15 years 6 months ago
An Object-Based Executable Model for Simulation of Real-Time Hw/Sw Systems
This paper describes a simulation technique for RealTime Hw/Sw systems based on an object executable model. It allows designers to seamlessly estimate and verify their solutions f...
Olivier Pasquier, Jean Paul Calvez
TOOLS
2000
IEEE
15 years 6 months ago
Design and Implementation of CORBA-Based Subscription Server
The standard CORBA operation invocation model supports synchronous, one-way, and deferred synchronous interactions between clients and servers. However, this model is too restrict...
R. Maheshwari, R. Fatoohi