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» Modelling Gene Regulatory Networks
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BMCBI
2005
124views more  BMCBI 2005»
15 years 3 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2010
183views more  BMCBI 2010»
15 years 3 months ago
SING: Subgraph search In Non-homogeneous Graphs
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
Raffaele Di Natale, Alfredo Ferro, Rosalba Giugno,...
ALIFE
1999
15 years 3 months ago
The Creatures Global Digital Ecosystem
An arti cial life entertainment-software product called Creatures was released in Europe in late 1996 and in the United States and Japan in mid-1997. When installed on a domestic c...
Dave Cliff, Stephen Grand
BMCBI
2004
128views more  BMCBI 2004»
15 years 3 months ago
Structural characterization of genomes by large scale sequence-structure threading: application of reliability analysis in struc
Background: We establish that the occurrence of protein folds among genomes can be accurately described with a Weibull function. Systems which exhibit Weibull character can be int...
Artem Cherkasov, Shannan J. Ho Sui, Robert C. Brun...
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BMCBI
2010
133views more  BMCBI 2010»
15 years 3 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang