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» Models and Methods in Comparative Genomics
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BMCBI
2006
124views more  BMCBI 2006»
13 years 11 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...
CPM
2004
Springer
108views Combinatorics» more  CPM 2004»
14 years 4 months ago
Quadratic Time Algorithms for Finding Common Intervals in Two and More Sequences
A popular approach in comparative genomics is to locate groups or clusters of orthologous genes in multiple genomes and to postulate functional association between the genes contai...
Thomas Schmidt, Jens Stoye
WABI
2001
Springer
134views Bioinformatics» more  WABI 2001»
14 years 3 months ago
Comparing Assemblies Using Fragments and Mate-Pairs
Using current technology, large consecutive stretches of DNA (such as whole chromosomes) are usually assembled from short fragments obtained by shotgun sequencing, or from fragment...
Daniel H. Huson, Aaron L. Halpern, Zhongwu Lai, Eu...
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 4 months ago
Prokaryote Phylogeny without Sequence Alignment: From Avoidance Signature to Composition Distance
A new and essentially simple method to reconstruct prokaryotic phylogenetic trees from their complete genome data without using sequence alignment is proposed. It is based on the ...
Bailin Hao, Ji Qi
RECOMB
2006
Springer
14 years 11 months ago
Sorting by Translocations Via Reversals Theory
Abstract. The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of...
Michal Ozery-Flato, Ron Shamir