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» Models and Methods in Comparative Genomics
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IMSCCS
2006
IEEE
14 years 3 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2007
125views more  BMCBI 2007»
13 years 10 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
13 years 10 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
BMCBI
2005
133views more  BMCBI 2005»
13 years 9 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
NAR
2002
110views more  NAR 2002»
13 years 9 months ago
Comparative Genometrics (CG): a database dedicated to biometric comparisons of whole genomes
The ever increasing rate at which whole genome sequences are becoming accessible to the scientific community has created an urgent need for tools enabling comparison of chromosome...
Claude-Alain H. Roten, Patrick Gamba, Jean-Luc Bar...