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BIOINFORMATICS
2011
14 years 10 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
153
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BMCBI
2011
14 years 10 months ago
R2R - software to speed the depiction of aesthetic consensus RNA secondary structures
Background: With continuing identification of novel structured noncoding RNAs, there is an increasing need to create schematic diagrams showing the consensus features of these mol...
Zasha Weinberg, Ronald R. Breaker
133
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BMCBI
2011
14 years 10 months ago
Revision history aware repositories of computational models of biological systems
Background: Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provid...
Andrew K. Miller, Tommy Yu, Randall Britten, Mike ...
BMCBI
2011
14 years 10 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
172
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BMCBI
2011
14 years 10 months ago
GCOD - GeneChip Oncology Database
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...
Fenglong Liu, Joseph White, Corina Antonescu, John...
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