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BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
BMCBI
2008
218views more  BMCBI 2008»
13 years 9 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...
BMCBI
2008
102views more  BMCBI 2008»
13 years 9 months ago
Ornithine decarboxylase antizyme finder (OAF): Fast and reliable detection of antizymes with frameshifts in mRNAs
Background: Ornithine decarboxylase antizymes are proteins which negatively regulate cellular polyamine levels via their affects on polyamine synthesis and cellular uptake. In vir...
Michaël Bekaert, Ivaylo P. Ivanov, John F. At...
BMCBI
2008
139views more  BMCBI 2008»
13 years 9 months ago
Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repea
Background: Identification of approximate tandem repeats is an important task of broad significance and still remains a challenging problem of computational genomics. Often there ...
Vladimir Paar, Nenad Pavin, Ivan Basar, Marija Ros...
BMCBI
2008
120views more  BMCBI 2008»
13 years 9 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
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