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RECOMB
2008
Springer
14 years 10 months ago
High-Resolution Modeling of Cellular Signaling Networks
A central challenge in systems biology is the reconstruction of biological networks from high-throughput data sets. A particularly difficult case of this is the inference of dynami...
Michael Baym, Chris Bakal, Norbert Perrimon, Bonni...
BMCBI
2006
108views more  BMCBI 2006»
13 years 10 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2005
67views more  BMCBI 2005»
13 years 9 months ago
Sequence signature analysis of chromosome identity in three Drosophila species
Background: All eukaryotic organisms need to distinguish each of their chromosomes. A few protein complexes have been described that recognise entire, specific chromosomes, for in...
Per Stenberg, Fredrik Pettersson, Anja O. Saura, A...
JCB
1998
92views more  JCB 1998»
13 years 9 months ago
Homology Detection via Family Pairwise Search
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
William Noble Grundy
NAR
2011
241views Computer Vision» more  NAR 2011»
13 years 4 months ago
PRIDB: a protein-RNA interface database
The Protein–RNA Interface Database (PRIDB) is a comprehensive database of protein–RNA interfaces extracted from complexes in the Protein Data Bank (PDB). It is designed to fac...
Benjamin A. Lewis, Rasna R. Walia, Michael Terribi...