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RECOMB
2005
Springer
14 years 7 months ago
Pairwise Local Alignment of Protein Interaction Networks Guided by Models of Evolution
Abstract. With ever increasing amount of available data on protein-protein interaction (PPI) networks and research revealing that these networks evolve at a modular level, discover...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
BMCBI
2006
150views more  BMCBI 2006»
13 years 7 months ago
Cluster analysis of protein array results via similarity of Gene Ontology annotation
Background: With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to t...
Cheryl Wolting, C. Jane McGlade, David Tritchler
ICDE
2007
IEEE
167views Database» more  ICDE 2007»
14 years 8 months ago
GString: A Novel Approach for Efficient Search in Graph Databases
Graphs are widely used for modeling complicated data, including chemical compounds, protein interactions, XML documents, and multimedia. Information retrieval against such data ca...
Haoliang Jiang, Haixun Wang, Philip S. Yu, Shuigen...
SAC
2006
ACM
14 years 1 months ago
Mining and analyzing the topological structure of protein-protein interaction networks
We report a comprehensive evaluation of the topological structure of protein-protein interaction (PPI) networks by mining and analyzing graphs constructed from the publicly availa...
Daniel Duanqing Wu, Xiaohua Hu