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ICFP
2010
ACM
13 years 8 months ago
Instance chains: type class programming without overlapping instances
Type classes have found a wide variety of uses in Haskell programs, from simple overloading of operators (such as equality or ordering) to complex invariants used to implement typ...
J. Garrett Morris, Mark P. Jones
BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
Detecting internally symmetric protein structures
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Changhoon Kim, Jodi Basner, Byungkook Lee
BMCBI
2010
116views more  BMCBI 2010»
13 years 7 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
BMCBI
2010
101views more  BMCBI 2010»
13 years 7 months ago
Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
M. S. Vijayabaskar, Saraswathi Vishveshwara
BMCBI
2007
100views more  BMCBI 2007»
13 years 7 months ago
PARE: A tool for comparing protein abundance and mRNA expression data
Background: Techniques for measuring protein abundance are rapidly advancing and we are now in a situation where we anticipate many protein abundance data sets will be available i...
Eric Z. Yu, Anne E. Counterman Burba, Mark Gerstei...