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BMCBI
2008
13 years 10 months ago
2008
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
BMCBI
2008
13 years 10 months ago
2008
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
BMCBI
2008
13 years 10 months ago
2008
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
BMCBI
2007
13 years 10 months ago
2007
Background: Biological information is commonly used to cluster or classify entities of interest such as genes, conditions, species or samples. However, different sources of data c...
BMCBI
2008
13 years 10 months ago
2008
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...