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BMCBI
2005
75views more  BMCBI 2005»
13 years 7 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
ESWA
2007
127views more  ESWA 2007»
13 years 7 months ago
Clustering support vector machines for protein local structure prediction
Understanding the sequence-to-structure relationship is a central task in bioinformatics research. Adequate knowledge about this relationship can potentially improve accuracy for ...
Wei Zhong, Jieyue He, Robert W. Harrison, Phang C....
GECCO
2008
Springer
164views Optimization» more  GECCO 2008»
13 years 8 months ago
Genetic algorithms with local search optimization for protein structure prediction problem
This paper presents a new Genetic Algorithm for Protein Structure Prediction problem in both 2D and 3D hydrophobichydrophilic lattice models, introduced in [1]. Our algorithm evol...
Igor Berenboym, Mireille Avigal
IJON
2010
199views more  IJON 2010»
13 years 5 months ago
DFS-generated pathways in GA crossover for protein structure prediction
Genetic Algorithms (GAs), as nondeterministic conformational search techniques, are promising for solving protein structure prediction (PSP) problems. The crossover operator of a ...
Tamjidul Hoque, Madhu Chetty, Andrew Lewis, Abdul ...
JCB
2000
146views more  JCB 2000»
13 years 7 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag