The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Abstract. A protein is a linear chain of amino acids that folds into a unique functional structure, called its native state. In this state, proteins show repeated substructures lik...
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...