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CLEF
2009
Springer
13 years 8 months ago
Morphological Analysis by Multiple Sequence Alignment
In biological sequence processing, Multiple Sequence Alignment (MSA) techniques capture information about long-distance dependencies and the three-dimensional structure of protein ...
Tzvetan Tchoukalov, Christian Monson, Brian Roark
RECOMB
2012
Springer
11 years 10 months ago
Estimating the Accuracy of Multiple Alignments and its Use in Parameter Advising
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
BMCBI
2008
109views more  BMCBI 2008»
13 years 7 months ago
The meaning of alignment: lessons from structural diversity
Background: Protein structural alignment provides a fundamental basis for deriving principles of functional and evolutionary relationships. It is routinely used for structural cla...
Walter Pirovano, K. Anton Feenstra, Jaap Heringa
ICML
2004
IEEE
14 years 8 months ago
A graphical model for protein secondary structure prediction
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
Wei Chu, Zoubin Ghahramani, David L. Wild
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
14 years 1 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert