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BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...
IPPS
2006
IEEE
14 years 1 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan
NAR
2000
109views more  NAR 2000»
13 years 7 months ago
The ASTRAL compendium for protein structure and sequence analysis
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included...
Steven E. Brenner, Patrice Koehl, Michael Levitt
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BIOINFORMATICS
2000
110views more  BIOINFORMATICS 2000»
13 years 7 months ago
ProtEST: protein multiple sequence alignments from expressed sequence tags
James A. Cuff, Ewan Birney, Michele E. Clamp, Geof...