It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re
ect the correct biolog...
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...