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CPM
1993
Springer
154views Combinatorics» more  CPM 1993»
13 years 11 months ago
On Suboptimal Alignments of Biological Sequences
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re ect the correct biolog...
Dalit Naor, Douglas L. Brutlag
NAR
2000
85views more  NAR 2000»
13 years 7 months ago
MitoNuc and MitoAln: two related databases of nuclear genes coding for mitochondrial proteins
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Graziano Pesole, Carmela Gissi, Domenico Catalano,...
WABI
2007
Springer
14 years 1 months ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
BMCBI
2007
153views more  BMCBI 2007»
13 years 7 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
14 years 2 months ago
ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...