Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
The Phospho.ELM resource (http://phospho.elm.eu .org) is a relational database designed to store in vivo and in vitro phosphorylation data extracted from the scientific literature...
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...