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» Multiple RNA Structure Alignment
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BMCBI
2008
122views more  BMCBI 2008»
13 years 10 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
BMCBI
2007
165views more  BMCBI 2007»
13 years 10 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 3 months ago
Graph Alignments: A New Concept to Detect Conserved Regions in Protein Active Sites
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
Nils Weskamp, Eyke Hüllermeier, Daniel Kuhn, ...
BMCBI
2004
141views more  BMCBI 2004»
13 years 9 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
WABI
2007
Springer
121views Bioinformatics» more  WABI 2007»
14 years 4 months ago
Seeded Tree Alignment and Planar Tanglegram Layout
The optimal transformation of one tree into another by means of elementary edit operations is an important algorithmic problem that has several interesting applications to computat...
Antoni Lozano, Ron Y. Pinter, Oleg Rokhlenko, Gabr...