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» Multiple RNA Structure Alignment
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BMCBI
2007
142views more  BMCBI 2007»
13 years 10 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
EMNLP
2009
13 years 7 months ago
Weighted Alignment Matrices for Statistical Machine Translation
Current statistical machine translation systems usually extract rules from bilingual corpora annotated with 1-best alignments. They are prone to learn noisy rules due to alignment...
Yang Liu, Tian Xia, Xinyan Xiao, Qun Liu
BMCBI
2007
112views more  BMCBI 2007»
13 years 10 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
RECOMB
2008
Springer
14 years 10 months ago
Fast and Accurate Alignment of Multiple Protein Networks
Comparative analysis of protein networks has proven to be a powerful approach for elucidating network structure and predicting protein function and interaction. A fundamental chall...
Maxim Kalaev, Vineet Bafna, Roded Sharan
BMCBI
2004
196views more  BMCBI 2004»
13 years 9 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar