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113
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BMCBI
2008
145views more  BMCBI 2008»
15 years 2 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
SDM
2003
SIAM
183views Data Mining» more  SDM 2003»
15 years 3 months ago
ApproxMAP: Approximate Mining of Consensus Sequential Patterns
Conventional sequential pattern mining methods may meet inherent difficulties in mining databases with long sequences and noise. They may generate a huge number of short and trivi...
Hye-Chung Kum, Jian Pei, Wei Wang 0010, Dean Dunca...
132
Voted
BMCBI
2004
115views more  BMCBI 2004»
15 years 2 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
121
Voted
BMCBI
2007
142views more  BMCBI 2007»
15 years 2 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...
BMCBI
2008
130views more  BMCBI 2008»
15 years 2 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi