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BMCBI
2004
177views more  BMCBI 2004»
13 years 10 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
CANDC
2006
ACM
13 years 11 months ago
Detecting and aligning peaks in mass spectrometry data with applications to MALDI
In this paper, we address the peak detection and alignment problem in the analysis of mass spectrometry data. To deal with the peak redundancy problem existing in the MALDI data a...
Weichuan Yu, Baolin Wu, Ning Lin, Kathy Stone, Ken...
NAR
2010
140views more  NAR 2010»
13 years 5 months ago
GUIDANCE: a web server for assessing alignment confidence scores
Evaluating the accuracy of multiple sequence alignment (MSA) is critical for virtually every comparative sequence analysis that uses an MSA as input. Here we present the GUIDANCE ...
Osnat Penn, Eyal Privman, Haim Ashkenazy, Giddy La...
HICSS
2003
IEEE
90views Biometrics» more  HICSS 2003»
14 years 4 months ago
A Prototype for Multiple Whole Genome Alignment
In this paper, we briefly describe a prototype of the software system we have developed for multiple whole genome alignment. To develop our algorithm, we have to solve several pr...
Jitender S. Deogun, Fangrui Ma, Jingyi Yang, Andre...
LSSC
2007
Springer
14 years 5 months ago
An Ant-Based Model for Multiple Sequence Alignment
Abstract. Multiple sequence alignment is a key process in today’s biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing so...
Frédéric Guinand, Yoann Pigné