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BMCBI
2008
176views more  BMCBI 2008»
13 years 11 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
JCB
2000
101views more  JCB 2000»
13 years 10 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...
RECOMB
2005
Springer
14 years 11 months ago
Using Multiple Alignments to Improve Gene Prediction
The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structur...
Samuel S. Gross, Michael R. Brent
COMPLIFE
2005
Springer
14 years 4 months ago
MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces
A protein-protein interface (PPI) is defined by a pair of regions of two interacting protein molecules that are linked by non-covalent bonds. Recognition of conserved 3D patterns ...
Alexandra Shulman-Peleg, Maxim Shatsky, Ruth Nussi...
CLEF
2009
Springer
14 years 1 days ago
Morphological Analysis by Multiple Sequence Alignment
In biological sequence processing, Multiple Sequence Alignment (MSA) techniques capture information about long-distance dependencies and the three-dimensional structure of protein ...
Tzvetan Tchoukalov, Christian Monson, Brian Roark