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» Multiple sequence alignment accuracy and evolutionary distan...
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BMCBI
2011
13 years 4 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
BMCBI
2010
142views more  BMCBI 2010»
13 years 10 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
ISBI
2007
IEEE
14 years 4 months ago
Multiview Registration of Cardiac Tagging Mri Images
This paper introduces a new method based on k-Nearest Neighbors Graphs (KNNG) for bringing into alignment multiple views of the same scene acquired at two different time points. T...
Estanislao Oubel, Mathieu De Craene, Mattia Gazzol...
BMCBI
2005
190views more  BMCBI 2005»
13 years 9 months ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu