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» Multiple sequence alignment by quantum genetic algorithm
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BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
RECOMB
2002
Springer
14 years 9 months ago
Comparison of minisatellites
In the class of repeated sequences that occur in DNA, minisatellites have been found polymorphic and became useful tools in genetic mapping and forensic studies. They consist of a...
Eric Rivals, Sèverine Bérard
CEC
2008
IEEE
14 years 3 months ago
A self-adaptive cellular memetic algorithm for the DNA fragment assembly problem
Abstract— The DNA fragment assembly problem is to reconstruct a DNA chain from multiple fragments that have previously been sequenced in a laboratory. This is a critical step in ...
Bernabé Dorronsoro, Enrique Alba, Gabriel L...
WABI
2007
Springer
14 years 2 months ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 6 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...