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» Multiple sequence alignment by quantum genetic algorithm
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ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 6 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
BMCBI
2005
73views more  BMCBI 2005»
13 years 8 months ago
Evaluation of Glycine max mRNA clusters
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...
Ronald L. Frank, Fikret Erçal
SODA
1998
ACM
157views Algorithms» more  SODA 1998»
13 years 10 months ago
A Polynomial Time Approximation Scheme for Minimum Routing Cost Spanning Trees
Given an undirected graph with nonnegative costs on the edges, the routing cost of any of its spanning trees is the sum over all pairs of vertices of the cost of the path between t...
Bang Ye Wu, Giuseppe Lancia, Vineet Bafna, Kun-Mao...
DAM
2007
91views more  DAM 2007»
13 years 8 months ago
Integer linear programming approaches for non-unique probe selection
In addition to their prevalent use for analyzing gene expression, DNA microarrays are an efficient tool for biological, medical, and industrial applications because of their abil...
Gunnar W. Klau, Sven Rahmann, Alexander Schliep, M...
IMSCCS
2006
IEEE
14 years 2 months ago
GenomeBlast: A Web Tool for Small Genome Comparison
Comparative genomics has become an essential approach for identifying homologous gene candidates and their functions, and for studying genome evolution. We developed GenomeBlast, ...
Guoqing Lu, Liying Jiang, Resa M. Kotalik, Thaine ...