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BMCBI
2006
116views more  BMCBI 2006»
13 years 11 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
A graph-search framework for associating gene identifiers with documents
Background: One step in the model organism database curation process is to find, for each article, the identifier of every gene discussed in the article. We consider a relaxation ...
William W. Cohen, Einat Minkov
BMCBI
2006
122views more  BMCBI 2006»
13 years 11 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2006
94views more  BMCBI 2006»
13 years 11 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...
BMCBI
2007
164views more  BMCBI 2007»
13 years 11 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason