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BMCBI
2006
187views more  BMCBI 2006»
13 years 10 months ago
Detecting outliers when fitting data with nonlinear regression - a new method based on robust nonlinear regression and the false
Background: Nonlinear regression, like linear regression, assumes that the scatter of data around the ideal curve follows a Gaussian or normal distribution. This assumption leads ...
Harvey J. Motulsky, Ronald E. Brown
BMCBI
2006
69views more  BMCBI 2006»
13 years 10 months ago
Retrieval with gene queries
Background: Accuracy of document retrieval from MEDLINE for gene queries is crucially important for many applications in bioinformatics. We explore five information retrieval-base...
Aditya Kumar Sehgal, Padmini Srinivasan
BMCBI
2006
97views more  BMCBI 2006»
13 years 10 months ago
A comparative analysis of the information content in long and short SAGE libraries
Background: Serial Analysis of Gene Expression (SAGE) is a powerful tool to determine gene expression profiles. Two types of SAGE libraries, ShortSAGE and LongSAGE, are classified...
Yi-Ju Li, Puting Xu, Xuejun Qin, Donald E. Schmech...
BMCBI
2006
84views more  BMCBI 2006»
13 years 10 months ago
Representation of target-bound drugs by computed conformers: implications for conformational libraries
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
Stefan Günther, Christian Senger, Elke Michal...
IDA
2008
Springer
13 years 10 months ago
Symbolic methodology for numeric data mining
Currently statistical and artificial neural network methods dominate in data mining applications. Alternative relational (symbolic) data mining methods have shown their effectivene...
Boris Kovalerchuk, Evgenii Vityaev