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BMCBI
2007
104views more  BMCBI 2007»
13 years 10 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
BMCBI
2007
151views more  BMCBI 2007»
13 years 10 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
BMCBI
2010
193views more  BMCBI 2010»
13 years 10 months ago
caGrid Workflow Toolkit: A Taverna based workflow tool for cancer Grid
Background: In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pi...
Wei Tan, Ravi K. Madduri, Aleksandra Nenadic, Stia...
BMCBI
2007
109views more  BMCBI 2007»
13 years 10 months ago
Seahawk: moving beyond HTML in Web-based bioinformatics analysis
Background: Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining multiple ...
Paul M. K. Gordon, Christoph W. Sensen
BMCBI
2008
144views more  BMCBI 2008»
13 years 10 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...