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» Multipolar representation of protein structure
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BMCBI
2010
154views more  BMCBI 2010»
13 years 8 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...
ISBI
2007
IEEE
14 years 2 months ago
Quantitative Representation of Three-dimensional Cell Culture Models
Three-dimensional mammary cell culture models offer new opportunities for the development of computational techniques for segmentation, localization, and multicellular organizatio...
Hang Chang, Catherine Park, Bahram Parvin
BMCBI
2006
84views more  BMCBI 2006»
13 years 7 months ago
Representation of target-bound drugs by computed conformers: implications for conformational libraries
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
Stefan Günther, Christian Senger, Elke Michal...
CORR
2010
Springer
144views Education» more  CORR 2010»
13 years 7 months ago
CLP-based protein fragment assembly
Abstract. The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments ar...
Alessandro Dal Palù, Agostino Dovier, Feder...