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124
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BMCBI
2008
15 years 2 months ago
2008
Background: Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of m...
127
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BMCBI
2007
15 years 2 months ago
2007
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
123
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BMCBI
2008
15 years 2 months ago
2008
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
124
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BMCBI
2007
15 years 2 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
138
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BMCBI
2008
15 years 2 months ago
2008
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...