Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
Jason W. H. Wong, Matthew J. Sullivan, Hugh M. Car...
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...